Preparation and motor potentials in chronic tic and Tourette syndromes.

نویسندگان

K O'Connor

M E Lavoie

M Robert

چکیده

Many studies have found that people with tic disorder show more difficulty when inhibiting an automated than a controlled response. Furthermore, although normal motor threshold and excitability are present, but reduced or impaired, motor inhibition seems manifest in patients with tic. In order to localize this inhibition impairment in tic disorder the present study examine two response-locked ERPs: the Bereitschaft (preparation BP) and the motor potentials (MP). The simple tic group showed faster BP latency and smaller amplitude than control and complex tic group and did not show a corresponding change in values with practice or with automated or controlled condition. The MP amplitudes revealed that whereas both controls and complex tic disorder showed a decrease in amplitude during control condition for both blocks, simple tic showed larger amplitude. Our ERP results are in agreement with RT results of a previous study. The explanation could lie with modulation in motor excitation inhibition circuits and seems worse in simple tics where the movements are more automatic and nonvoluntary.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

اثر بخشی آموزش فنون وارونه سازی عادت در کاهش شدت ، فراوانی ، پیچیدگی و تداخل سندرم تورت و تیک های حرکتی

Background & Aims: Tic disorders are a group of conditions with onset in the developmental period. The disorders produce impairments of functioning. The goal of this study was to investigate the effectiveness of habit reversal techniques training(HRT) on reduction of intensity, frequency, complexity and interference of tourette syndrome and motor tics. Materials & Methods: This study wa...

متن کامل

Motor excitability during movement preparation in Tourette syndrome

Tourette syndrome (TS) is a neurodevelopmental disorder characterized by the occurrence of motor and vocal tics. TS has been linked to the impaired operation of cortical-striatal-thalamic-cortical circuits that give rise to hyper-excitability of cortical motor areas, which may be exacerbated by dysfunctional intra-cortical inhibitory mechanisms. That said, many individuals gain control over the...

متن کامل

Effect of Rhythmic Music Auditory Stimulation

Tourette Syndrome (TS) is a chronic neurologic disorder characterized by the childhood onset of multiple motor and phonic tics that wax and wanes over time [1]. The syndrome is common (1%) and the aetiology is complex (mostly genetic) and 90% of people have co-morbid psychiatric disorders and reduced quality of life [2]. In facts Tourette syndrome is the most common cause of tics. Other tic dis...

متن کامل

Association between pre- and perinatal exposures and Tourette syndrome or chronic tic disorder in the ALSPAC cohort†

BACKGROUND Tourette syndrome and chronic tic disorder are heritable but aetiologically complex. Although environment plays a role in their development, existing studies of non-genetic risk factors are inconsistent. AIMS To examine the association between pre- and perinatal exposures and Tourette syndrome/chronic tic disorder in the Avon Longitudinal Study of Parents and Children (ALSPAC) pros...

متن کامل